COVID-19, Updated March 22, 2020There is NO known COVID-19 treatment confirmed with randomized controlled trials.
Yet doctors from around the world are using (or have used) some drugs for treatment in China, Italy, South Korea and others.
There are great doctors on the internet who give us information on the latest research papers.
Dr. Seheult and Medcram Team (website), and YouTube Channel
Dr. John Campbell (YouTube) gives great information on Coronavirus with his very appropriate "Healthcare Of the People, By the People and For the People" approach.
One video is of particular interest for the treatment of coronavirus:
Coronavirus Pandemic Update 35: New Outbreaks & Travel Restrictions, Possible COVID-19 Treatments mentions an important recent research paper from China, a treatment with hydroxychloroquine (a malaria drug) as well as potential benefits of Quercetin (with a big questionmark since there is nothing on it yet on COVID-19 treatment). He mentions that these may work because of their ability to get zinc inside the cells.
Dr. John Campbell's video on Immunity and Vitamin D shows research based evidence how maintaining healthy levels of vitamin D may help immune system, not directly for COVID19, but general immune system performance against some infections.
There are also many other drugs that are repurposed and are used by doctors around the world, among them: antivirals like Kaletra used for HIV treatment, Remdesivir developed in US by Gilead Sciences. Some German scientists proposed a pancreatitis drug developed in Japan, Camostat ( Casmostat for COVID-19?)
The antiviral drug, called Favipiravir or Avigan, showed positive outcomes in clinical trials as reported by China)
Intravenous Vitamin C has been used in some Intensive Care Units in China and around the world, no published results yet.
There is major debate about Angiotensin Receptors in the context of Covid19 now, as to whether they are helpful or not.
Hydroxichloroquine (HCQ) plus azythromycin an antibiotic with some antiviral properties has shown encouraging results as shown by Didier Raoult from France in a small study. Currently this combination are being administered (and sometimes used) by doctors in many countries, like Dr. Tale Tung Chen from Spain.
Since there is no drug developed for COVID-19 doctors' best bet would be to use repurposed drugs. This is not a new approach, reporpusing drugs work in some cancers and other medical conditions too as seen in research papers listed on this website.
COVID-19 StatisticsSince I am not a doctor I do NOT give medical advice but list information given by doctors and research papers.
However, I am good in math, with advanced degree in Mechanical ENgineering and I can give some layman number infomation of my own (not disease spread modeling!).
In general, I think one the best approaches for a rough calculation of infected but not tested people out there could be the serious/critical cases + deaths per number of infected people.
This is a layman approach and NOT an eloborate statistical model involving many parameters.
Needless to say, one may say that this ratio is also unknown hence this way of thinking may not show anything.
I think that the two best cases of data is from cruiseship Diamond Princess where we have full testing info on relatively older age group (cruise passengers) and we have South Korea where extremely well and extensive testing is done on general population which showed most cases to be largely young followers of a cult group centered around Daegu.
Based on these two best datasets, and the number of new cases added each day, I can do a rough calculation (could be incorrect) on the number of infected people out there without any symptoms.
This could give Italy figures to be much higher than the reported cases.
However, I have also learned that health officials in the US, give higher figures for their own state (for example Ohio, Washington) based on much more eloborate models. So my rough calculation could well be -underestimating- infection figures.